DPP4 anticorps
Aperçu rapide pour DPP4 anticorps (ABIN3025647)
Antigène
Voir toutes DPP4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Aucune reactivité croisée
- Porc, Mouton
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Purification
- Protein G affinity chromatography
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Immunogène
- A human T cell clone was used as the immunogen for the CD26 antibody.
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Isotype
- IgG2b kappa
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Indications d'application
- Optimal dilution of the CD26 antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Immunohistochemistry (Frozen Only): 0.5-1 μg/mL for 30 min at RT
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store the CD26 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- DPP4 (Dipeptidyl-Peptidase 4 (DPP4))
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Autre désignation
- CD26
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Sujet
- Recognizes a glycoprotein of 110 kDa, identified as CD26 (Workshop VI, Code: N-L039). It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this mAb reacts with only glycosylated CD26, but not with the deglycosylated form. It does not prevent ADA binding to CD26.
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Pathways
- Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity
Antigène
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